Transport across the choroid plexus epithelium
نویسندگان
چکیده
منابع مشابه
Transport across the choroid plexus epithelium.
The choroid plexus epithelium is a secretory epithelium par excellence. However, this is perhaps not the most prominent reason for the massive interest in this modest-sized tissue residing inside the brain ventricles. Most likely, the dominant reason for extensive studies of the choroid plexus is the identification of this epithelium as the source of the majority of intraventricular cerebrospin...
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Methotrexate-3H was accumulated in vitro against a con centration gradient by the rabbit choroid plexus. This accumu lation was energy dependent, inhibited by metabolic inhibitors, and exhibited self-saturation and competitive inhibition. Several folie acid analogs with a 4-amino group were inhibitors of this accumulation, while folie and folinic acid, compounds which do not contain a 4-amino g...
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BACKGROUND The Wnt and BMP signaling pathways are involved in the morphogenesis of both gastrointestinal and choroid plexus epithelium. In the intestine, Wnt signaling represses the expression of the tumor suppressor gene CDX2 via SOX9, a transcription factor, which is also expressed in the choroid plexus. Recently, an inverse correlation between CDX2 expression and tumor grade, tumor stage and...
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ژورنال
عنوان ژورنال: American Journal of Physiology-Cell Physiology
سال: 2017
ISSN: 0363-6143,1522-1563
DOI: 10.1152/ajpcell.00041.2017